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Xi Chen Selected Research

Insulin Resistance

12/2023Thrombospondin 2 is a novel biomarker of essential hypertension and associated with nocturnal Na+ excretion and insulin resistance.
8/2023Predictive values of metabolic score for insulin resistance on risk of major adverse cardiovascular events and comparison with other insulin resistance indices among Chinese with and without diabetes mellitus: Results from the 4C cohort study.
1/2023Orally administered octacosanol improves liver insulin resistance in high-fat diet-fed mice through the reconstruction of the gut microbiota structure and inhibition of the TLR4/NF-κB inflammatory pathway.
1/2023Chronic physiologic hyperglycemia impairs insulin-mediated suppression of plasma glucagon concentration in healthy humans.
1/2023Long-Term High-Fat Diet Decreases Renal Insulin-Degrading Enzyme Expression and Function by Inhibiting the PPARγ Pathway.
9/2022Structure and hypoglycemic effect of a neutral polysaccharide isolated from sea cucumber Stichopus japonicus.
1/2022Resveratrol regulates insulin resistance to improve the glycolytic pathway by activating SIRT2 in PCOS granulosa cells.
1/2022Association of Homocysteine and Insulin Resistance with Increased Risk of Mortality in a Nondiabetic Population: Third National Health and Nutrition Examination Survey.
1/2022Response to Letter to the Editor from Roy et al: "Impaired Suppression of Glucagon in Obese Subjects Parallels Decline in Insulin Sensitivity and Beta-Cell Function".
12/2021Serum branched-chain amino acids modifies the associations between air pollutants and insulin resistance.
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Xi Chen Research Topics

Disease

748Neoplasms (Cancer)
12/2024 - 09/2002
209Inflammation (Inflammations)
12/2024 - 12/2007
198Infections
05/2024 - 03/2002
106Neoplasm Metastasis (Metastasis)
05/2024 - 01/2003
96Breast Neoplasms (Breast Cancer)
01/2024 - 11/2008
88Carcinogenesis
02/2024 - 03/2006
78Hepatocellular Carcinoma (Hepatoma)
03/2024 - 12/2010
75Colorectal Neoplasms (Colorectal Cancer)
04/2024 - 03/2006
69Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2024 - 10/2008
63Lung Neoplasms (Lung Cancer)
07/2023 - 10/2008
55Prostatic Neoplasms (Prostate Cancer)
05/2024 - 04/2004
50Hypoxia (Hypoxemia)
05/2024 - 02/2006
50Stomach Neoplasms (Stomach Cancer)
03/2024 - 01/2005
48Alzheimer Disease (Alzheimer's Disease)
05/2024 - 04/2004
47Obesity
01/2024 - 11/2011
45Parkinson Disease (Parkinson's Disease)
05/2024 - 12/2003
44Myocardial Infarction
05/2023 - 08/2004
41Wounds and Injuries (Trauma)
04/2024 - 02/2005
39COVID-19
05/2024 - 01/2020
37Pain (Aches)
05/2024 - 11/2013
36Adenocarcinoma of Lung
01/2024 - 05/2009
36Body Weight (Weight, Body)
11/2023 - 12/2007
35Fibrosis (Cirrhosis)
04/2024 - 04/2010
34Cardiovascular Diseases (Cardiovascular Disease)
01/2024 - 08/2006
33Carcinoma (Carcinomatosis)
02/2024 - 09/2002
33Type 2 Diabetes Mellitus (MODY)
12/2023 - 06/2013
32Hypertension (High Blood Pressure)
10/2023 - 09/2007
31Glioma (Gliomas)
04/2024 - 12/2016
31Tuberculosis (Tuberculoses)
02/2024 - 01/2002
31Cognitive Dysfunction
02/2024 - 03/2013
29Stroke (Strokes)
02/2024 - 04/2014
29Insulin Resistance
12/2023 - 05/2013
29Esophageal Squamous Cell Carcinoma
12/2023 - 12/2010
28Nasopharyngeal Carcinoma
04/2024 - 01/2006
28Pancreatic Neoplasms (Pancreatic Cancer)
04/2024 - 01/2003
26Necrosis
04/2024 - 04/2010
26Neurodegenerative Diseases (Neurodegenerative Disease)
03/2024 - 07/2007
26Atherosclerosis
12/2023 - 11/2006
25Colonic Neoplasms (Colon Cancer)
04/2024 - 06/2006
24Ischemic Stroke
05/2024 - 10/2016
24Chronic Obstructive Pulmonary Disease (COPD)
04/2024 - 09/2014
24Sepsis (Septicemia)
04/2024 - 04/2009
24Ovarian Neoplasms (Ovarian Cancer)
10/2023 - 06/2012
23Osteoporosis
04/2024 - 01/2014
22Disease Progression
05/2024 - 04/2004
22Colitis
05/2024 - 12/2012
21Burns
03/2024 - 01/2007
21Virus Diseases (Viral Diseases)
03/2024 - 03/2011
21Non-alcoholic Fatty Liver Disease
02/2024 - 09/2009
21Hemorrhage
10/2023 - 02/2008
20Mitochondrial Diseases (Mitochondrial Disease)
12/2023 - 04/2004
20Heart Failure
06/2023 - 04/2014

Drug/Important Bio-Agent (IBA)

282Proteins (Proteins, Gene)FDA Link
05/2024 - 11/2003
202Biomarkers (Surrogate Marker)IBA
04/2024 - 06/2008
161MicroRNAs (MicroRNA)IBA
01/2024 - 06/2008
101Messenger RNA (mRNA)IBA
03/2024 - 04/2004
100CytokinesIBA
05/2024 - 04/2003
69Long Noncoding RNAIBA
02/2024 - 01/2017
62RNA (Ribonucleic Acid)IBA
04/2024 - 06/2010
57EnzymesIBA
02/2024 - 03/2003
50Glucose (Dextrose)FDA LinkGeneric
01/2024 - 09/2005
49LipidsIBA
05/2024 - 08/2012
47AntigensIBA
01/2024 - 03/2003
46Small Interfering RNA (siRNA)IBA
02/2024 - 05/2010
45AntibodiesIBA
08/2023 - 01/2008
44DNA (Deoxyribonucleic Acid)IBA
04/2024 - 09/2004
42VaccinesIBA
01/2024 - 04/2003
37Therapeutic UsesIBA
04/2024 - 06/2005
35Polysaccharides (Glycans)IBA
02/2024 - 02/2006
34CateninsIBA
02/2024 - 03/2011
33Interleukin-6 (Interleukin 6)IBA
05/2024 - 02/2015
33LigandsIBA
04/2024 - 03/2003
32Retinaldehyde (Retinal)IBA
05/2024 - 01/2014
32Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2024 - 09/2006
32Indicators and Reagents (Reagents)IBA
06/2023 - 12/2006
30Immune Checkpoint InhibitorsIBA
04/2024 - 01/2019
30Phosphotransferases (Kinase)IBA
03/2024 - 04/2011
30Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
09/2023 - 04/2003
27Oxygen (Dioxygen)IBA
05/2024 - 09/2010
26Peptides (Polypeptides)IBA
05/2024 - 05/2008
26Reactive Oxygen Species (Oxygen Radicals)IBA
03/2024 - 11/2003
26Transcription Factors (Transcription Factor)IBA
11/2023 - 03/2002
25CollagenIBA
04/2024 - 08/2004
23Anti-Bacterial Agents (Antibiotics)IBA
04/2024 - 07/2011
22salicylhydroxamic acid (SHAM)IBA
07/2023 - 08/2005
21Antiviral Agents (Antivirals)IBA
10/2023 - 01/2011
20Circular RNAIBA
05/2024 - 01/2018
20InterleukinsIBA
02/2024 - 01/2014
20CholesterolIBA
10/2023 - 10/2006
20Insulin (Novolin)FDA Link
01/2023 - 08/2011
20InterferonsIBA
01/2023 - 03/2013
19Cisplatin (Platino)FDA LinkGeneric
12/2024 - 09/2010

Therapy/Procedure

345Therapeutics
12/2024 - 09/2002
107Drug Therapy (Chemotherapy)
03/2024 - 01/2003
74Immunotherapy
04/2024 - 06/2011
52Radiotherapy
03/2024 - 09/2002
33Chinese Traditional Medicine (Traditional Chinese Medicine)
12/2024 - 07/2006
24Chemoradiotherapy
12/2023 - 12/2016
22Aftercare (After-Treatment)
03/2024 - 09/2006
21Transplantation
11/2023 - 06/2005